Appendix 2: Evidence Summaries for Grading the Recommendations

Four Recommendations have been made based on the following key questions -

  1. What is the effectiveness of hypofractionated radiotherapy compared to conventionally fractionated radiotherapy for the treatment of early breast cancer?

    In patients with early breast cancer who require post-operative whole breast radiotherapy who meet the following criteria:
    - aged 50 years and over
    - with pathological stage T1-2, N0, M0
    - who have undergone breast conserving surgery, with clear surgical margins

    Read more

     
  2. What is the effectiveness of hypofractionated radiotherapy compared to conventionally fractionated radiotherapy for the treatment of early breast cancer?

    For patients who do not meet the selection criteria for Recommendation 1

    Read more

     
  3. What is the optimal schedule for hypofractionated radiotherapy for the treatment of early breast cancer?

     Read more

     
  4. What is the safety of hypofractionated radiotherapy compared to conventionally fractionated radiotherapy for the treatment of early breast cancer?

     Read more