Metastatic cancer is also known as advanced or secondary cancer.

Locally advanced breast cancer is defined by the presence of a tumour that has one of the following characteristics: ‘peau d’orange’, skin ulceration, or fixation to the underlying intercostal or serratus anterior muscles or bones of the chest wall or inflammatory carcinoma. Breast cancer that has spread to distant sites is referred to as metastatic breast cancer.

The below guidelines for the management of advanced breast cancer, and associated topic-specific guideline updates, are designed to assist in decision making by women and their doctors.

Clinical practice guidelines​

• Recommendations for the management of central nervous system (CNS) metastases in women with secondary breast cancer
  Publication date: 2014
  Please note: these topic-specific guidelines are now available as online guidelines.