Types of bladder cancer

A A

There are 3 main types of bladder cancer. These are named after the cell type in which the cancer first develops. 

  • Urothelial carcinoma (or transitional cell carcinoma) is the most common type of bladder cancer, making up more than 80–90% of bladder cancers [1]. It starts in the cells in the inside layer of the bladder wall (urothelial cells). This type of cancer sometimes occurs in the ureters and kidneys [2], and can move into the muscle wall of the bladder or to other parts of the body [3].  
  • Squamous cell carcinoma is the next most common type of bladder cancer, making up about 1–2% of bladder cancers. It starts in the thin, flat cells that line the bladder (squamous cells) and is more likely to be invasive [4]. This type of cancer may develop after a long-term infection or irritation [5].  
  • Adenocarcinoma is a rare type of bladder cancer, making up 1% of bladder cancers. It starts in glandular cells that line the bladder and is likely to be invasive [6].  

Other rare types of bladder cancer include sarcoma, small cell carcinoma, plasmacytoid carcinoma and micropapillary carcinoma [7]. These occur rarely in less than 1% of bladder cancer cases.