Sleep disturbance: Complementary therapies

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Background
Grading of Clinical Practice Recommendations
Clinical Practice Recommendations and Practice Points
Summary of Evidence - Methodology
Summary of Evidence - Introduction
Summary of Evidence - Vasomotor symptoms
Summary of Evidence - Sleep disturbance
- Sleep disturbance: Pharmacological interventions
- Sleep disturbance: Hormonal interventions
- Sleep disturbance: Psychological and physical interventions
- Sleep disturbance: Complementary therapies
Summary of Evidence - Vulvovaginal symptoms and sexual function
Summary of Evidence - Depression and anxiety
Summary of Evidence - Mood and emotional wellbeing
Summary of Evidence - Mental health
Summary of Evidence - Global quality of life
Summary of Evidence - Breast cancer recurrence
Strengths and Weaknesses of the Evidence
Unanswered Questions Regarding Treatments of Interest
International Guidelines
Ongoing and Additional Trials of Interest
Drug Contraindications and Side Effects
Evidence Matrix
References
Acknowledgements
Additional Information
Appendix 1: Grading Methodology
Appendix 2: Evidence Summaries
Appendix 3: Recommendation Grading Forms

Phytoestrogens

One RCT (with an unknown risk of bias) identified in a Systematic Review (with a moderate risk of bias) in peri- and early postmenopausal women (with hot flushes and at least one co-occurring symptom) found that an isoflavone combination significantly reduced insomnia at 12 weeks; other trials found that soy and other isoflavones did not significantly improve sleep symptoms.⁷⁵ [ES55]

Omega-3 fatty acids

One RCT (with a low risk of bias) in peri- and postmenopausal women reported no significant effect on sleep quality and insomnia with omega-3 fatty acid supplementation compared to placebo.⁷⁶ [ES56]

Vitamin E

One RCT (with a moderate risk of bias) in women after breast cancer found that Vitamin E (800 IU/d for 12 weeks) was inferior to gabapentin (900mg/d for 12 weeks) at reducing sleep disturbance.³³ [ES24]

Sleep disturbance: Complementary therapies