Symptoms of cancer of unknown primary vary, depending on where the cancer has spread in the body. 

Some people may have no symptoms. But symptoms may include: 

• a lump or thickening in any part of the body 
• a new or unusual pain that doesn’t go away, including in the chest or abdomen 
• headaches 
• fatigue or weakness 
• shortness of breath 
• swollen lymph nodes, especially in the neck, underarm, chest or groin 
• change in bladder habits (such as more frequent urination) or change in bowel habits (such as constipation or diarrhoea) 
• fever 
• night sweats 
• loss of appetite or unexplained weight loss. 

There are many conditions that can cause these symptoms, not just cancer. If you have any of these symptoms, you should discuss them with your doctor.