Important unanswered questions about the use of first-line chemotherapy for the treatment of women with epithelial ovarian cancer may be addressed in clinical trials investigating:
- Generalisability of dose-dense chemotherapy across a range of populations.
- Role of novel biological/molecular therapies in the first-line treatment of women with epithelial ovarian cancer.
- Chemotherapy regimens in older women, particularly in patients who are frail or have comorbidities.
- Specific chemotherapy requirements for women with epithelial ovarian cancer who are obese.